
LyoWave TurboDry™ is a tunable high-frequency microwave heating platform designed to accelerate the manufacturing process for frozen and lyophilized pharmaceutical systems.
Utilizing cutting-edge solid-state RF amplifier technology, TurboDry™ technology delivers proven performance for small molecules, vaccines, biologics, reagents, and medical devices.
Operating at frequencies specifically targeting water ice, TurboDryTM combines proprietary electronic mixing and metasurface scattering elements to achieve an electric field uniformity over 5 times greater than traditional 2.45 GHz microwave systems at a fraction of the power.
Dielectric heating eliminates the need for conduction from temperature-controlled shelves and abolishes throughput bottlenecks placed on novel dosage forms such as lyobeads, nested vials and syringes, bulk powders, and shell/spinfrozen systems.
Specialized optical temperature sensors combined with a proprietary closed-loop control architecture provide accurate and robust control over product temperature during drying and thawing operations.
Modular and minimally invasive, TurboDryTM easily retrofits onto new and existing laboratory and pilot-scale freeze-drying systems in minutes.
• >12 GHz output at power levels up to 100W per module.
• Patented electromagnetic mixing improves heating uniformity by 5x relative to 2.45GHz systems.
• Standard Modbus communication interface provides monitoring and control capability.
• Local or remote operation.
• Optional optical probes provide calibrated temperature measurement accuracy of +/- 0.2°C and resolution of 0.1°C.
• Enhanced electromagentic mixing using patented metasurface scattering technology and modulation.
• Non-invasive infrared imaging of product temperature in real time.
• Time-lapse image logging and user-defined point tracking for simplified post-processing and analysis.
• RF power and frequency modulation based on real-time feedback from temperature sensors.
• Precise control of product temperature to accelerate development time and optimize the drying process.


LyoWave has partnered with Millrock Technology to bring a limited number of qRF microwave sources to REVO freeze-drying systems for development purposes. Contact us if you’re interested in participating in this program.
Sign Me Up!• Conventional vial drying (>1.5-2x speedup).
• Nested RTU vials and syringes.
• Spin/shell frozen containers.
• Microsphere pellets and lyobeads (>5x speedup).
• Spray-frozen powders.
• Bulk drug product or substance.
• Reagents for molecular diagnostics freeze-dried in PCR tubes and well plates.
• Bulk tissue freeze-drying.
• Rapid and uniform thawing (>5x speedup) of biologics to reduce agglomeration induced by cryoconcentration.
SBIR Phase I: Scaling Up Tunable High-Frequency Microwave Heating for Pharmaceutical and Biologics Manufacturing
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