TurboDry™

Tunable RF Heating Platform for Pharmaceutical Freeze-Drying and Thawing
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TurboDry™ product rendering

How It Works

LyoWave TurboDry™ is a tunable high-frequency microwave heating platform designed to accelerate the manufacturing process for frozen and lyophilized pharmaceutical systems.

Utilizing cutting-edge solid-state RF amplifier technology, TurboDry™ technology delivers proven performance for small molecules, vaccines, biologics, reagents, and medical devices.

TurboDry™ Advantages

Uniformity and Efficiency

Operating at frequencies specifically targeting water ice, TurboDryTM combines proprietary electronic mixing and metasurface scattering elements to achieve an electric field uniformity over 5 times greater than traditional 2.45 GHz microwave systems at a fraction of the power.

Volumetric Heating

Dielectric heating eliminates the need for conduction from temperature-controlled shelves and abolishes throughput bottlenecks placed on novel dosage forms such as lyobeads, nested vials and syringes, bulk powders, and shell/spinfrozen systems.

Precision Control

Specialized optical temperature sensors combined with a proprietary closed-loop control architecture provide accurate and robust control over product temperature during drying and thawing operations.

Seamless Integration

Modular and minimally invasive, TurboDryTM easily retrofits onto new and existing laboratory and pilot-scale freeze-drying systems in minutes.

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Key Features

Solid-State RF Source

• >12 GHz output at power levels up to 100W per module.

• Patented electromagnetic mixing improves heating uniformity by 5x relative to 2.45GHz systems.

Standardized Communication

• Standard Modbus communication interface provides monitoring and control capability.

• Local or remote operation.

Temperature Measurement

• Optional optical probes provide calibrated temperature measurement accuracy of +/- 0.2°C and resolution of 0.1°C.

Advanced Field Mixing

• Enhanced electromagentic mixing using patented metasurface scattering technology and modulation.

Remote Sensing

• Non-invasive infrared imaging of product temperature in real time.

• Time-lapse image logging and user-defined point tracking for simplified post-processing and analysis.

Closed-Loop Control

• RF power and frequency modulation based on real-time feedback from temperature sensors.

• Precise control of product temperature to accelerate development time and optimize the drying process.

Lyowave logoMillrock Technologies logo

LyoWave has partnered with Millrock Technology to bring a limited number of qRF microwave sources to REVO freeze-drying systems for development purposes. Contact us if you’re interested in participating in this program.

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Application Notes

Vials and Syringes

• Conventional vial drying (>1.5-2x speedup).

• Nested RTU vials and syringes.

• Spin/shell frozen containers.

Bulk Materials and Powders

• Microsphere pellets and lyobeads (>5x speedup).

• Spray-frozen powders.

• Bulk drug product or substance.

Diagnostic Reagents and Tissues

• Reagents for molecular diagnostics freeze-dried in PCR tubes and well plates.

• Bulk tissue freeze-drying.

Drug Substance

• Rapid and uniform thawing (>5x speedup) of biologics to reduce agglomeration induced by cryoconcentration.

We're Award Winning

SBIR Phase I: Scaling Up Tunable High-Frequency Microwave Heating for Pharmaceutical and Biologics Manufacturing

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Product Specfications

TurboDry™

Frequency~13–15 GHz
Power30W or 60W
ModulationSine, sawtooth, random, constant
InterfaceModbus TCP
Dimensions24.6" × 24.3" × 8.5"
Electrical120V / 10A
Lyowave TurboDry™ Data Brochure
TurboDry™ Spec Sheet

Download our brochure for more detailed information.

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