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LyoWave TurboThaw™ is a controlled-rate thawing platform designed to reduce processing time for bulk frozen API by up to 4X.
Compatible with primary packaging from 30mL to 4L and most industry-standard formats, TurboThaw™ integrates across multiple development pipelines simultaneously.
Utilizing LyoWave's high-frequency microwave heating technology, TurboThaw™ delivers proven performance for biologics, vaccines, cell therapies, and bulk drug substance.
Volumetric RF heating thaws bulk materials up to 4x faster than conventional ambient methods, eliminating the cryoconcentration and aggregation risks associated with slow, uneven thawing.
Precise temperature control protects against localized overheating and protein aggregation - maintaining critical quality attributes for biologics, mAbs, and cell therapies.
TurboThaw™ uses the same closed-loop optical temperature sensing architecture as TurboDry™ - real-time feedback ensures product temperature stays within validated thaw parameters.
The TurboThaw™ modular design is directly compatible with existing cold chain and thaw workflows, minimizing disruption to your current process.
• >12 GHz output at power levels up to 100W per module.
• Patented electromagnetic mixing improves thawing uniformity by up to 4x relative to 2.45GHz systems.
• Standard Modbus communication interface provides monitoring and control capability.
• Local or remote operation.
• Optional optical probes provide calibrated temperature measurement accuracy of +/- 0.2°C and resolution of 0.1°C.
• Enhanced electromagentic mixing using patented metasurface scattering technology and modulation.
• Non-invasive infrared imaging of product temperature in real time.
• Time-lapse image logging and user-defined point tracking for simplified post-processing and analysis.
• RF power and frequency modulation based on real-time feedback from temperature sensors.
• Precise control of product temperature to accelerate development time and optimize the thawing process.
LyoWave has partnered with Millrock Technology to bring a limited number of microwave sources to REVO freeze-drying systems for development purposes. Contact us if you’re interested in participating in this program.
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