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Press release
June 16, 2026

LyoWave installs microwave-assisted lyophilization and thawing technology at Simtra BioPharma Solutions

Since June 2026, LyoWave's full product suite - TurboDry™, TurboThaw™, and LyoVision™ - has been running at Simtra BioPharma Solutions in Bloomington, Indiana, marking the first CDMO deployment of our microwave-assisted lyophilization and thawing technology.

The LyoWave team in front of a Millrock REVO freeze dryer fitted with a LyoWave RF source
LyoWave team on-site at Simtra BioPharma Solutions, installing TurboDry™, TurboThaw™, and LyoVision™ for the first CDMO deployment of our microwave-assisted lyophilization.
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WEST LAFAYETTE, Ind. — LyoWave has installed its full product suite - TurboDry™, TurboThaw™, and LyoVision™ - at Simtra BioPharma Solutions in Bloomington, Indiana, marking the first deployment of LyoWave's microwave-assisted lyophilization technology at a contract development and manufacturing organization (CDMO).

LyoWave team installing technology in Simtra lab
LyoWave team on-site at Simtra BioPharma Solutions, installing TurboDry™, TurboThaw™, and LyoVision™ for the first CDMO deployment of our microwave-assisted lyophilization.

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The installation gives Simtra hands-on access to evaluate how LyoWave's technology performs within a live CDMO workflow. The Simtra team is now running its own experiments on the equipment to assess fit for their process needs - from accelerated primary drying with TurboDry™, to controlled-rate thawing with TurboThaw™, to real-time thermal imaging and process analytical technology with LyoVision™.

TurboDry™, TurboThaw™, and LyoVision™ installed on a Millrock Revo Pro
TurboDry™, TurboThaw™, and LyoVision™ installed on a Millrock Revo Pro

The project is supported by a BioCAN grant through Heartland BioWorks, an initiative funded by the U.S. Economic Development Administration and administered by the Applied Research Institute (ARI) to connect Indiana biotech innovators with the state's CDMO and lab infrastructure. The grant is helping offset the cost of bringing LyoWave's equipment into a commercial product development pipeline for the first time.

For LyoWave, the Simtra installation is a proof point for a broader thesis: that RF/microwave-assisted lyophilization can move from lab-scale demonstration into real CDMO operations. As Simtra's evaluation progresses, LyoWave expects to share more on how the technology is compatible with a diverse set of injectible biologics.

Follow LyoWave on LinkedIn for updates as the Simtra evaluation progresses.

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About LyoWave

LyoWave, Inc. was founded in 2023 as a spinout of Purdue University's LyoHUB, an industry-university center advancing the science and technology of pharmaceutical freeze-drying. Based at the Kurz Purdue Technology Center in West Lafayette, Indiana, LyoWave develops RF-assisted lyophilization, thawing, and thermal imaging systems for pharmaceutical manufacturing. Learn more at lyowave.com.

Media contact

info@lyowave.com

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